The Endocannabinoid system

The Endocannabinoid system

Mee Staff

As a CBD user, you’ve likely heard about the endocannabinoid system and CBD. When we first learn about CBD, the words ‘endocannabinoid’, ‘receptors’ and ‘enzymes’ get thrown around a lot. But as everyday folk, grasping exactly what these mean can be a little difficult. Many of us begin our CBD journey enthralled by the abilities of this natural compound without completely grasping the science behind it. But, the good news is, as CBD nerds, we have all the information you need to know. The endocannabinoid system is how Mee CBD gets to show its superpowers, and we’re talking you through it in this simple and easy to digest guide. 

What is the endocannabinoid system?

The endocannabinoid system is a biological system that runs throughout the body. Although research is still in the preliminary stages, studies show the endocannabinoid system (ESC) controls numerous bodily functions. The ESC works by sending signals around the body through a complex system of receptors, enzymes and endocannabinoids.

Endocannabinoid system functions

The endocannabinoid system promotes homeostasis, this is the running of your internal body. Studies show the ECS can assist:

● Digestion

● Metabolism

● Appetite

● Pain

● Inflammation

● Mood

● Stress

● Anxiety

● Memory

● Learning

● Cardiovascular system

● Sleep

● Muscle development and formation

● Liver function

● Bone growth

● The reproductive system

● Skin health

● Nerve function

If something isn’t going according to plan, the ECS works hard to get things back on track. For example, if we injure ourselves, the endocannabinoid system will promote inflammation while helping the body recover. Research is still in the early stages, thus the full capabilities and responsibility of the ECS remains unknown.

the-endocannabinoid-system-and-cbd

How does the endocannabinoid system work?

The enzymes, receptors and endocannabinoids work together in the endocannabinoid system. You’re likely familiar with the term ‘cannabinoid’ as a Mee CBD user.

Endocannabinoids are cannabinoids created by the body. So far, scientists are familiar with two prominent endocannabinoids: anandamide (AEA) and 2-arachidonoylglyerol (2-AG). AEA regulates feeding behaviours such as appetite, taste and is often referred to as the bliss molecule for the associated heartwarming feeling it has been shown to provide. 2-AG influences emotional responses, pain receptors and energy levels.

After carrying out their functions, enzymes break down the endocannabinoids in the body. As the ECS has helped the body achieve balance, we don’t want the endocannabinoids continuing to make changes. Fatty acid amide hydrolase breaks down AEA endocannabinoids. And monoacylglycerol acid lipase destroys 2-AG.

CBD is also a cannabinoid but unlike AEA and 1-AG, CBD is not created in the body. Rather it needs to be ingested much like a vitamin. CBD then enables, among other good things, the endocannabinoids in your body to interact more effectively with the endocannabinoid system.

The ECS is a collection of cannabinoid receptors that bind to with cannabinoids that are either endo (made by the body) or not.ie.g.CBD. Our two main cannabinoid receptors are called the CB1 and CB2 receptors. Different cannabinoids react with different receptors and some cannabinoids react with both. Each cannabinoid therefore creates a unique effect on the body.

For example, if a cannabinoid binds to the CB1 receptor it can help regulate brain chemical function. And a different cannabinoid may bind to a CB2 receptor to indicate inflammation is happening. The scientific studies into the scope and function of the 114 known cannabinoids on human body is in its infancy. CBD, CBDa, THC, THCa, CBG, CBC, CBN and THCVa are currently the most researched cannabinoids, and are showing profoundly interesting therapeutic benefits.

The endocannabinoid is a very clever system, but sometimes it needs assistance—this is where CBD can help. What is endocannabinoid deficiency?

Clinical Endocannabinoid Deficiency (CED) is considered to be a potential reason for difficult-to-characterise psychosomatic pathologies. Psychosomatic pathologies are psychological conditions that become physical conditions without explanation.

Endocannabinoid System and CBD

The exact science behind CBD and the endocannabinoid system is not fully understood. However, research shows CBD interacts with the ECS to calm the symptoms of anxiety and depression, reduce inflammation, and increase the efficiency of the endocannabinoids (the internally created cannabinoids).

Many believe CBD works by stopping endocannabinoids being broken down (by those powerful enzymes), so the endocannabinoids can have a longer, more intense effect. Another common hypothesis is that CBD binds to a currently unknown receptor that causes it to influence a range of bodily functions.

The endocannabinoid system is pretty impressive. If you want to see what your body is capable of, enhance your daily functions and promote a healthy body and mind, CBD could be the remedy for you. CBD helps us make the most of our body’s endocannabinoid system.

Mee CBD is a great place to start due to our highly advanced scientific formulation that is easy to integrate into any existing daily drinking ritual – like a cup of tea.

To learn about more ways CBD interacts with your endocannabinoid system, you can read the Mee CBD blog. We cover everything from knee pain to anxiety, so you can fully understand the transformative abilities of introducing CBD to your daily routine. Check our range of water-soluble CBD products.

https://www.healthline.com/health/endocannabinoid-system#functions

https://www.medicalnewstoday.com/articles/endocannabinoid#production

https://en.wikipedia.org/wiki/Endocannabinoid_system#:~:text=The%20endocannabinoid%20system%20(ECS)%20is,system%20(including%20the%20brain)%20and

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